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Results: 11 - 20 of 58 results for: GENE
GENE 210 Genomics and Personalized Medicine (DBIO 220)
Principles of genetics underlying associations between genetic variants and disease susceptibility and drug response. Topics include: genetic and environmental risk factors for complex genetic disorders; design and interpretation of genome-wide association studies; pharmacogenetics; full genome sequencing for disease gene discovery; population structure and genetic ancestry; use of personal geneti.... More Description for GENE 210
GENE 211 Genomics
The goal of this course is to explore different genomic approaches and technologies, to learn how they work from a molecular biology view point, and to understand how they can be applied to understanding biological systems. In addition, we teach material on how the data generated from these approaches can be analyzed, from an algorithmic perspective. The papers that are discussed are a mixture of .... More Description for GENE 211
Terms: 2018-2019 Winter | Units: Array 3 | Grading: Medical Option (Med-Ltr-CR/NC)
GENE 212 Introduction to Biomedical Informatics Research Methodology (BIOE 212, BIOMEDIN 212, CS 272)
Capstone Biomedical Informatics (BMI) experience. Hands-on software building. Student teams conceive, design, specify, implement, evaluate, and report on a software project in the domain of biomedicine. Creating written proposals, peer review, providing status reports, and preparing final reports. Issues related to research reproducibility. Guest lectures from professional biomedical informatics s.... More Description for GENE 212
Terms: 2018-2019 Spring | Units: 3-5 | Grading: Medical Option (Med-Ltr-CR/NC)
GENE 214 Representations and Algorithms for Computational Molecular Biology (BIOE 214, BIOMEDIN 214, CS 274)
Topics: introduction to bioinformatics and computational biology, algorithms for alignment of biological sequences and structures, computing with strings, phylogenetic tree construction, hidden Markov models, basic structural computations on proteins, protein structure prediction, protein threading techniques, homology modeling, molecular dynamics and energy minimization, statistical analysis of 3.... More Description for GENE 214
Terms: 2018-2019 Autumn | Units: 3-4 | Grading: Medical Option (Med-Ltr-CR/NC)
GENE 215 Frontiers in Biological Research (BIOC 215, DBIO 215)
Students analyze cutting edge science, develop a logical framework for evaluating evidence and models, and enhance their ability to design original research through exposure to experimental tools and strategies. The class runs in parallel with the Frontiers in Biological Research seminar series. Students and faculty meet on the Tuesday preceding each seminar to discuss a landmark paper in the sp.... More Description for GENE 215
Terms: 2018-2019 Spring 2018-2019 Winter 2018-2019 Autumn | Units: Array 1 | Repeatable for credit | Grading: Medical Satisfactory/No Credit
GENE 216 Practical Considerations and Industry Perspective on Academic-Industry Collaborations
Provides an overview, fundamentals and practical considerations for different aspects of academic-industry collaborations by inviting current industrial experts to share their views and to answer questions. The different aspects include collaboration models, proposal building, IP right sharing, funding opportunities, sabbatical and internship in industry, industry job searching, etc. This class al.... More Description for GENE 216
Terms: 2018-2019 Spring | Units: 1 | Grading: Medical Option (Med-Ltr-CR/NC)
GENE 217 Translational Bioinformatics (BIOE 217, BIOMEDIN 217, CS 275)
Computational methods for the translation of biomedical data into diagnostic, prognostic, and therapeutic applications in medicine. Topics: multi-scale omics data generation and analysis, utility and limitations of public biomedical resources, machine learning and data mining, issues and opportunities in drug discovery, and mobile/digital health solutions. Case studies and course project. Prerequi.... More Description for GENE 217
Terms: 2018-2019 Winter | Units: 4 | Grading: Medical Option (Med-Ltr-CR/NC)
GENE 218 Computational Analysis of Biological Information: Introduction to Python for Biologists (MI 218, PATH 218)
Computational tools for processing, interpretation, communication, and archiving of biological information. Emphasis is on sequence and digital microscopy/image analysis. Intended for biological and clinical trainees without substantial programming experience.
GENE 221 Current Issues in Aging
Current research literature on genetic mechanisms of aging in animals and human beings. Topics include: mitochondria mutations, insulin-like signaling, sirtuins, aging in flies and worms, stem cells, human progeria, and centenarian studies. Prerequisite: GENE 203, 205 or BIOS 200.
Terms: 2018-2019 Spring | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
GENE 224 Principles of Pharmacogenomics (BIOMEDIN 224)
This course is an introduction to pharmacogenomics, including the relevant pharmacology, genomics, experimental methods (sequencing, expression, genotyping), data analysis methods and bioinformatics. The course reviews key gene classes (e.g., cytochromes, transporters) and key drugs (e.g., warfarin, clopidogrel, statins, cancer drugs) in the field. Resources for pharmacogenomics (e.g., PharmGKB,.... More Description for GENE 224
Terms: 2018-2019 Winter 2018-2019 Autumn 2018-2019 Spring 2018-2019 Summer | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
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