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Results: 1 - 10 of 71 results for: BIOS
BIOS 200 Foundations in Experimental Biology
This course is divided into two 3-week cycles. During the first cycle, students will be developing a 2-page original research proposal, which may be used for NSF or other fellowship applications. In the second cycle, students will work in small teams and will be mentored by faculty to develop an original research project for oral presentation. Skills emphasized include: 1) reading for breadth an.... More Description for BIOS 200
Terms: 2017-2018 Autumn | Units: 5 | Grading: Medical Satisfactory/No Credit
BIOS 201 Next Generation Sequencing and Applications
Usher in the golden age of biological discovery with next generation sequencing (NGS) through its wide spectrum of applications. Modules include general introduction of Next Generation Sequencing (NGS) technologies, applications of these sequencing technologies, caveats and comparisons with previous approaches, analysis and interpretation of sequencing data, principles of tools and resources and .... More Description for BIOS 201
Terms: 2017-2018 Winter | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Devlin, M. (GP)
BIOS 202 Hippocampal Field Potentials, an Introduction to CNS in Vitro Electrophysiology
Enrollment limited to graduate students in the School of Medicine; undergraduates may enroll with instructor consent. Introduces students to theory and practice of in vitro CNS electrophysiology. Lectures cover basic electrical and electrode theory, hippocampal anatomy, interpretation of these potentials, common pitfalls and misinterpretations, design of experiments using field potentials and oth.... More Description for BIOS 202
Instructors: Devlin, M. (GP)
BIOS 203 Introduction to Atomistic Simulations for Biochemical Applications
Theory and application of atomistic simulations needed to model and understand systems of biological relevance (proteins, DNA, small molecule therapeutic drug properties) for beginners. Topics: molecular interactions and classical force fields, first principles energy approaches, molecular dynamics, rare event and transition-state finding techniques, protein folding, and solvation methods. Hands-o.... More Description for BIOS 203
Instructors: Devlin, M. (GP)
BIOS 204 Practical Tutorial on the Modeling of Signal Transduction Motifs
Basics of ordinary differential equation modeling of signal transduction motifs, small circuits of regulatory proteins and genes that serve as building blocks of complex regulatory circuits. Morning session covers numerical modeling experiments. Afternoon session explores theory underpinning that day's modeling session. Modeling done using Mathematica, Standard Edition provided to enrolled stud.... More Description for BIOS 204
Terms: 2017-2018 Spring | Units: 3 | Grading: Medical Satisfactory/No Credit
Instructors: Devlin, M. (GP)
BIOS 205 Introduction to R for Data Analysis
Autumn quarter enrollment limited to ADVANCE students; instructor consent required for enrollment. Topics include: basics of R (widely used, open-source programming and data analysis environment) programming language and data structures, reading/writing files, graphics tools for figure generation, basic statistical and regression operations, survey of relevant R library packages. Interactive form.... More Description for BIOS 205
Terms: 2017-2018 Winter 2017-2018 Spring 2017-2018 Autumn | Units: 1 | Grading: Medical Satisfactory/No Credit
BIOS 206 Stem Cells and Regeneration: Transitioning from Basic Research to Clinical Therapies
Presents emerging therapies based on stem cell by the scientists leading these pioneering efforts, including academic and industry-based groups. Provides hands-on instruction in laboratory methods valuable in development of stem cell therapies.
BIOS 207 Interdisciplinary Approaches to Biochemistry: Single Molecule Biophysics to Clinical Outcomes
Interdisciplinary analysis from basic biochemistry and biophysics to clinical outcomes of disease states and potential therapeutic interventions. Focus on cardiac system. Single molecule biophysics and classical enzyme kinetics and use of induced pluripotent stem (iPS) cells and single cell studies lay foundation for discussions of effects of cardiomyopathy mutations on heart function. Analytic.... More Description for BIOS 207
BIOS 208 Computational Macromolecule Structure Modeling
Concepts, workflow, and methodology of protein structure modeling presented through short lectures followed by hands-on exercises with the Rosetta software package. Several problem types demonstrate how to formulate and test well-defined hypotheses, in addition to the design and engineering of structure, function, and interactions.
BIOS 209 Practical Protein NMR Structure Determination
Work toward solving a high-resolution 3D structure from unprocessed NMR data acquired on a small well-characterized protein. Short lectures followed by hands-on computer exercises demonstrate best practices for data processing, spectra interpretation, and structure calculation with attention to troubleshooting and validation methods. Students should be familiar with fundamental concepts of prote.... More Description for BIOS 209
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