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Results: 41 - 50 of 98 results for: BIOE
BIOE 231 Protein Engineering (BIOE 331)
The design and engineering of biomolecules emphasizing proteins, antibodies, and enzymes. Combinatorial and rational methodologies, protein structure and function, and biophysical analyses of modified biomolecules. Clinically relevant examples from the literature and biotech industry. Prerequisite: basic biochemistry. Winter, Cochran
Terms: 2018-2019 Spring | Units: 3 | Grading: Letter (ABCD/NP)
BIOE 236 Biophysical Mechanisms of Innate Immunity
The innate immune system provides our first line of defense against infections of all kinds as well as cancer. Innate immune effectors, e.g. host defense peptides are deployed by numerous cell types (neutrophils, macrophages, NK cells, as well as epithelial cells, keratinocytes, and others) and attack by biophysical mechanisms of action. Disorders of innate immunity are increasingly being implicat.... More Description for BIOE 236
BIOE 238 Principles and Tools for Metrology in Biology
A practical introduction to the science of measurement. Emphasis is on the tools used to parse a biological measurement problem. Students will learn to identify and quantitatively address the critical sources of variability and bias using the core concepts of uncertainty, traceability, and validation. Case studies will illustrate use of metrology in current and emergent bioscience and engineering .... More Description for BIOE 238
BIOE 241 Biological Macromolecules (BIOC 241, BIOPHYS 241, SBIO 241)
The physical and chemical basis of macromolecular function. Topics include: forces that stabilize macromolecular structure and their complexes; thermodynamics and statistical mechanics of macromolecular folding, binding, and allostery; diffusional processes; kinetics of enzymatic processes; the relationship of these principles to practical application in experimental design and interpretation. The.... More Description for BIOE 241
New technologies from gene editing to networked computing have already transformed our economic and social structures and are increasingly changing what it means to be human. What role has law played in regulating and shaping these technologies? And what role can and should it play in the future? This seminar will consider these and related questions, focusing on new forms of networked production,.... More Description for BIOE 242
BIOE 244 Advanced Frameworks and Approaches for Engineering Integrated Genetic Systems
Concepts and techniques for the design and implementation of engineered genetic systems. Topics covered include the quantitative exploration of tools that support (a) molecular component engineering, (b) abstraction and composition of functional genetic devices, (c) use of control and dynamical systems theory in device and systems design, (d) treatment of molecular "noise", (e) integrat.... More Description for BIOE 244
Terms: 2018-2019 Spring | Units: 4 | Grading: Letter or Credit/No Credit
BIOE 248 Neuroengineering Laboratory (NSUR 248)
Laboratory course exploring the basics of neuroelectrophysiology, neuroengineering, and closed-loop neural decoding. Course will use low-cost electrophysiological amplifying equipment and a real-time recording and computational system to measure neural action potentials from invertebrates, record electromyography from people, and create real-time neural decoders for closed-loop human movement cont.... More Description for BIOE 248
BIOE 256 Technology Assessment and Regulation of Medical Devices (MS&E 256)
Regulatory approval and reimbursement for new health technologies are critical success factors for product commercialization. This course explores the regulatory and payer environment in the U.S. and abroad, as well as common methods of health technology assessment. Students will learn frameworks to identify factors relevant to the adoption of new health technologies, and the management of those f.... More Description for BIOE 256
Terms: 2018-2019 Spring | Units: 3 | Grading: Letter or Credit/No Credit
Instructors: Pietzsch, J. (PI)
BIOE 260 Tissue Engineering (ORTHO 260)
Principles of tissue engineering and design strategies for practical applications for tissue repair. Topics include tissue morphogenesis, stem cells, biomaterials, controlled drug and gene delivery, and paper discussions. Students will learn skills for lab research through interactive lectures, paper discussions and research proposal development. Students work in small teams to work on develop res.... More Description for BIOE 260
Terms: 2018-2019 Spring | Units: 4 | Grading: Letter (ABCD/NP)
BIOE 261 Principles and Practice of Stem Cell Engineering (NSUR 261)
Quantitative models used to characterize incorporation of new cells into existing tissues emphasizing pluripotent cells such as embryonic and neural stem cells. Molecular methods to control stem cell decisions to self-renew, differentiate, die, or become quiescent. Practical, industrial, and ethical aspects of stem cell technology application. Final projects: team-reviewed grants and business prop.... More Description for BIOE 261
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